RNA Details
Disease Name
multiple sclerosis
Tissue
brain
RNA Symbol
GSDMB
RNA ID
RNA Type
circRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR
Target
NA
Pathway
NA
PubMed ID
Title
The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis
Year
2017
Function
"Both alternative splicing (AS) isoforms and the identified ecircRNA were significantly dysregulated in peripheral blood mononuclear cells of relapsing-remitting multiple sclerosis (MS) patients compared to controls, further supporting the notion that aberrant RNA metabolism is a characteristic feature of the disease."